Background: Blood pressure and its diurnal variation is severely distorted in acute cerebral infarction. And it is difficult to evaluate the hemodynamic significance of blood pressure in this condition. Therefore, we investigated the ambulatory blood pressure monitoring data concerned with echocardigraphic left ventricular mass index to validate the hemodynamic significance of blood pressure in acute cerebral infarction patients.
Method: Retrospectively, ambulatory blood pressure monitoring and echocardiographic data were collected from 46 patients within 3 days after the acute cerebral infarction. Nocturnal blood pressure fall was calculated according to the individual sleeping interval and it was expressed in percentage (%) of daytime systolic blood pressure. Dipper was defined as 10% or more decrease in nocturnal systolic blood pressure. 86% of the patients were able to carry out ordinary daily activity.
Results: 1) 24hour mean blood pressure was 137.3±20 mmHg in systole, and 78.6± 11.5 mmHg in diastole, and mean blood pressure load was 47.4% in systole and, 24.1% in diastole in acute cerebral infarction. Normal blood pressure was observed in 48% of patients of acute cerebral infarction and non-dipper was observed in 73.9%.
2) Left ventricular mass index was 127±29.7 g/m2 and 58.7% of the patients showed left ventricular hypertrophy in echocardiographic assessment.
3) LVMI had a correlation with daytime systolic blood pressure (r=0.38, p=0.01), nighttime systolic blood pressure (r=0.35, p=0.02) and daytime systolic blood pressure load (r=0.58, p=0.002), but not with mean diastolic blood pressure (r=0.09, p=0.6).
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